PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets

The importance of identifying VEGF-independent pathways in pathological angiogenesis is increasingly recognized as a result of the emerging drug resistance to anti-VEGF therapies. PDGF-CC is the third member of the PDGF family discovered after more than two decades of studies on PDGF-AA and PDGF-BB....

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Detalhes bibliográficos
Main Authors: Hou, Xu, Kumar, Anil, Lee, Chunsik, Wang, Bin, Arjunan, Pachiappan, Dong, Lijin, Maminishkis, Arvydas, Tang, Zhongshu, Li, Yang, Zhang, Fan, Zhang, Shi-Zhuang, Wardega, Piotr, Chakrabarty, Sagarika, Liu, Baoying, Wu, Zhijian, Colosi, Peter, Fariss, Robert N., Lennartsson, Johan, Nussenblatt, Robert, Gutkind, J. Silvio, Cao, Yihai, Li, Xuri
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901428/
https://ncbi.nlm.nih.gov/pubmed/20566880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004143107
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