Platelet-derived Growth Factor-DD Targeting Arrests Pathological Angiogenesis by Modulating Glycogen Synthase Kinase-3β Phosphorylation

Platelet-derived growth factor-DD (PDGF-DD) is a recently discovered member of the PDGF family. The role of PDGF-DD in pathological angiogenesis and the underlying cellular and molecular mechanisms remain largely unexplored. In this study, using different animal models, we showed that PDGF-DD expres...

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Hauptverfasser: Kumar, Anil, Hou, Xu, Lee, Chunsik, Li, Yang, Maminishkis, Arvydas, Tang, Zhongshu, Zhang, Fan, Langer, Harald F., Arjunan, Pachiappan, Dong, Lijin, Wu, Zhijian, Zhu, Linda Y., Wang, Lianchun, Min, Wang, Colosi, Peter, Chavakis, Triantafyllos, Li, Xuri
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865282/
https://ncbi.nlm.nih.gov/pubmed/20231273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113787
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