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Prospects for Antigen-Specific Tolerance Based Therapies for the Treatment of Multiple Sclerosis

A primary focus in autoimmunity is the breakdown of central and peripheral tolerance resulting in the survival and eventual activation of autoreactive T cells. As CD4(+) T cells are key contributors to the underlying pathogenic mechanisms responsible for the onset and progression of most autoimmune...

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Detalles Bibliográficos
Main Authors: Turley, Danielle M., Miller, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901403/
https://ncbi.nlm.nih.gov/pubmed/19130025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/400_2008_13
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