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Prospects for Antigen-Specific Tolerance Based Therapies for the Treatment of Multiple Sclerosis
A primary focus in autoimmunity is the breakdown of central and peripheral tolerance resulting in the survival and eventual activation of autoreactive T cells. As CD4(+) T cells are key contributors to the underlying pathogenic mechanisms responsible for the onset and progression of most autoimmune...
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Format: | Artigo |
Jezik: | Inglês |
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2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901403/ https://ncbi.nlm.nih.gov/pubmed/19130025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/400_2008_13 |
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