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Worldwide Distribution of the MYH9 Kidney Disease Susceptibility Alleles and Haplotypes: Evidence of Historical Selection in Africa
MYH9 was recently identified as renal susceptibility gene (OR 3–8, p<10(−8)) for major forms of kidney disease disproportionately affecting individuals of African descent. The risk haplotype (E-1) occurs at much higher frequencies in African Americans (≥60%) than in European Americans (<4%), r...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901326/ https://ncbi.nlm.nih.gov/pubmed/20634883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011474 |
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