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Maternal angiotensinogen (AGT) haplotypes, fetal renin (REN) haplotypes and risk of preeclampsia; estimation of gene-gene interaction from family-triad data

BACKGROUND: Preeclampsia is a debilitating disorder affecting approximately 3% of pregnant women in the Western world. Although inconclusive, current evidence suggests that the renin-angiotensin system may be involved in hypertension. Therefore, our objective was to determine whether the genes for p...

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Detalhes bibliográficos
Main Authors: Vefring, Hege K, Wee, Line, Jugessur, Astanand, Gjessing, Håkon K, Nilsen, Stein T, Lie, Rolv T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901215/
https://ncbi.nlm.nih.gov/pubmed/20537141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-90
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