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Nuclear reprogramming to a pluripotent state by three approaches

The stable states of differentiated cells are now known to be controlled by dynamic mechanisms that can easily be perturbed. An adult cell can therefore be reprogrammed, altering its pattern of gene expression, and hence its fate, to that typical of another cell type. This has been shown by three di...

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Detalhes bibliográficos
Main Authors: Yamanaka, Shinya, Blau, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901154/
https://ncbi.nlm.nih.gov/pubmed/20535199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09229
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