The Plasmodium eukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

Sporozoites, the invasive form of malaria parasites transmitted by mosquitoes, are quiescent while in the insect salivary glands. Sporozoites only differentiate inside of the hepatocytes of the mammalian host. We show that sporozoite latency is an active process controlled by a eukaryotic initiation...

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Bibliographic Details
Main Authors: Zhang, Min, Fennell, Clare, Ranford-Cartwright, Lisa, Sakthivel, Ramanavelan, Gueirard, Pascale, Meister, Stephan, Caspi, Anat, Doerig, Christian, Nussenzweig, Ruth S., Tuteja, Renu, Sullivan, William J., Roos, David S., Fontoura, Beatriz M.A., Ménard, Robert, Winzeler, Elizabeth A., Nussenzweig, Victor
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901070/
https://ncbi.nlm.nih.gov/pubmed/20584882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091975
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