RNA Internal Loops with Tandem AG Pairs: The Structure of the 5′GAGU/3′UGAG Loop Can Be Dramatically Different from Others, Including 5′AAGU/3′UGAA

[Image: see text] Thermodynamic stabilities of 2 × 2 nucleotide tandem AG internal loops in RNA range from −1.3 to +3.4 kcal/mol at 37 °C and are not predicted well with a hydrogen-bonding model. To provide structural information to facilitate development of more sophisticated models for the sequenc...

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Hauptverfasser: Hammond, Nicholas B., Tolbert, Blanton S., Kierzek, Ryszard, Turner, Douglas H., Kennedy, Scott D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900907/
https://ncbi.nlm.nih.gov/pubmed/20481618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100332r
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