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Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum

Phosphatidylinositol (3,4,5)-triphosphate (PtdInsP(3)) mediates intracellular signaling for directional sensing and pseudopod extension at the leading edge of migrating cells during chemotaxis. How this PtdInsP(3) signal is translated into remodeling of the actin cytoskeleton is poorly understood. H...

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Detalhes bibliográficos
Main Authors: Zhang, Pingbo, Wang, Yu, Sesaki, Hiromi, Iijima, Miho
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900710/
https://ncbi.nlm.nih.gov/pubmed/20547830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006153107
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