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mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

Synthesis of tRNA and 5S rRNA by RNA polymerase (pol) III is regulated by the mTOR pathway in mammalian cells. The mTOR kinase localizes to tRNA and 5S rRNA genes, providing an opportunity for direct control. Its presence at these sites can be explained by interaction with TFIIIC, a DNA-binding fact...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kantidakis, Theodoros, Ramsbottom, Ben A., Birch, Joanna L., Dowding, Sarah N., White, Robert J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900655/
https://ncbi.nlm.nih.gov/pubmed/20543138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005188107
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