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Activated Hepatic Stellate Cells Induce Tumor Progression of Neoplastic Hepatocytes in a TGF-β Dependent Fashion

The development of hepatocellular carcinomas from malignant hepatocytes is frequently associated with intra- and peritumoral accumulation of connective tissue arising from activated hepatic stellate cells. For both tumorigenesis and hepatic fibrogenesis, transforming growth factor (TGF)-β signaling...

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Autori principali: MIKULA, M., PROELL, V., FISCHER, A.N.M., MIKULITS, W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900580/
https://ncbi.nlm.nih.gov/pubmed/16883581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.20772
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