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α-Synuclein mediates alterations in membrane conductance: a potential role for α-synuclein oligomers in cell vulnerability

α-Synuclein has been linked to the pathogenesis of Parkinson's disease and other synucleinopathies through its propensity to form toxic oligomers. The exact mechanism for oligomeric synuclein-directed cell vulnerability has not been fully elucidated but one hypothesis portends the formation of...

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Autori principali: Feng, Li Rebekah, Federoff, Howard J., Vicini, Stefano, Maguire-Zeiss, Kathleen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900531/
https://ncbi.nlm.nih.gov/pubmed/20550572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07266.x
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