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Reducing Modeling Error of Graphical Methods for Estimating Volume of Distribution Measurements in PIB-PET study

Graphical analysis methods are widely used in positron emission tomography quantification because of their simplicity and model independence. But they may, particularly for reversible kinetics, lead to bias in the estimated parameters. The source of the bias is commonly attributed to noise in the da...

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Main Authors: Guo, Hongbin, Renaut, Rosemary A, Chen, Kewei, Reiman, Eric M
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900488/
https://ncbi.nlm.nih.gov/pubmed/20493196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2010.05.002
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