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Mass spectrometric identification of oxidative modifications of tryptophan residues in proteins: chemical artifact or post-translational modification?

Oxidative modification of tryptophan to kynurenine (KYN) and N-formyl kynurenine (NFK) has been described in mitochondrial proteins associated with redox metabolism, and in human cataract lenses. To a large extent, however, previously reported identifications of these modifications were performed us...

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Main Authors: Perdivara, Irina, Deterding, Leesa J., Przybylski, Michael, Tomer, Kenneth B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900464/
https://ncbi.nlm.nih.gov/pubmed/20219394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2010.02.016
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