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Simvastatin Improves Clinical Scores In A Rabbit Multiple Infarct Ischemic Stroke Model: Synergism With A ROCK Inhibitor, But Not The Thrombolytic Tissue Plasminogen Activator

Statins have pleiotropic neuroprotective effects in the central nervous system. In this study, we assessed the pharmacological effects of simvastatin on measures of behavior in New Zealand white rabbits embolized using a suspension of small-sized blood clots. For these studies, simvastatin was admin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lapchak, Paul A., Han, Moon Ku
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900417/
https://ncbi.nlm.nih.gov/pubmed/20493175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.05.035
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