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Novel Alexa Fluor-488 Labeled Antagonist of the A(2A) Adenosine Receptor: Application to a Fluorescence Polarization-Based Receptor Binding Assay
Fluorescence polarization (FP) assay has many advantages over the traditional radioreceptor binding studies. We developed an A(2A) adenosine receptor (AR) FP assay using a newly synthesized fluorescent antagonist of the A(2A)AR (MRS5346), a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine deri...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900413/ https://ncbi.nlm.nih.gov/pubmed/20438717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.04.027 |
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