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Genomic profiling of tumor initiating prostatospheres

BACKGROUND: The cancer stem cell (CSC) hypothesis proposes that a population of tumor cells bearing stem cell properties is responsible for the origin and maintenance of tumors. Normal and cancer stem cells possess the ability to grow in vitro as self-renewing spheres, but the molecular basis of thi...

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Detalhes bibliográficos
Main Authors: Duhagon, Maria Ana, Hurt, Elaine M, Sotelo-Silveira, Jose R, Zhang, Xiaohu, Farrar, William L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900264/
https://ncbi.nlm.nih.gov/pubmed/20500816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-324
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