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Invasive Prostate Cancer Cells Are Tumor Initiating Cells That Have A Stem Cell-Like Genomic Signature

Development of metastasis is a leading cause of cancer-induced death. Acquisition of an invasive tumor cell phenotype suggests loss of cell adhesion and basement membrane breakdown during a process termed epithelial-to-mesenchymal transition (EMT). Recently, cancer stem cells (CSC) were discovered t...

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Detalhes bibliográficos
Main Authors: Klarmann, George J., Hurt, Elaine M., Mathews, Lesley A., Zhang, Xiaohu, Duhagon, Maria A., Mistree, Tashan, Thomas, Suneetha B., Farrar, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782741/
https://ncbi.nlm.nih.gov/pubmed/19221883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-009-9242-2
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