Loss of Androgen Receptor-Dependent Growth Suppression by Prostate Cancer Cells Can Occur Independently from Acquiring Oncogenic Addiction to Androgen Receptor Signaling

The conversion of androgen receptor (AR) signaling as a mechanism of growth suppression of normal prostate epithelial cells to that of growth stimulation in prostate cancer cells is often associated with AR mutation, amplification and over-expression. Thus, down-regulation of AR signaling is commonl...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: D'Antonio, Jason M., Vander Griend, Donald J., Antony, Lizamma, Ndikuyeze, George, Dalrymple, Susan L., Koochekpour, Shahriar, Isaacs, John T.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2010
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900211/
https://ncbi.nlm.nih.gov/pubmed/20628607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011475
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