Lanean...

Binding of fluorinated phenylalanine α-factor analogs to Ste2p: Evidence for a cation-π binding interaction between a peptide ligand and its cognate G protein-coupled receptor

Ste2p, a G protein-coupled receptor (GPCR), binds α-factor, WHWLQLKPGQPMY, a tridecapeptide pheromone secreted by yeast cells. Upon α-factor binding, Ste2p undergoes conformational changes activating a signal transduction system through its associated heterotrimeric G protein leading to the arrest o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tantry, Subramanyam, Ding, Fa-Xiang, Dumont, Mark, Becker, Jeffrey M., Naider, Fred
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900185/
https://ncbi.nlm.nih.gov/pubmed/20420459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100280f
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!