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Reduced Endoplasmic Reticulum Luminal Calcium Links Saturated Fatty Acid-Mediated Endoplasmic Reticulum Stress and Cell Death in Liver Cells

Chronic exposure to elevated free fatty acids, in particular long chain saturated fatty acids, provokes endoplasmic reticulum (ER) stress and cell death in a number of cell types. The perturbations to the ER that instigate ER stress and activation of the unfolded protein in response to fatty acids i...

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Bibliographic Details
Main Authors: Wei, Yuren, Wang, Dong, Gentile, Christopher L., Pagliassotti, Michael J.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899892/
https://ncbi.nlm.nih.gov/pubmed/19444596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0142-1
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