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Saturated Fatty Acid-Induced Cytotoxicity in Liver Cells Does Not Involve Phosphatase and Tensin Homologue Deleted on Chromosome 10

Liver specific deletion of the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN) induces steatosis and hypersensitivity to insulin. Saturated fatty acids, which induce endoplasmic reticulum stress and cell death, appear to increase PTEN, whereas unsaturated fatty acid...

詳細記述

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書誌詳細
主要な著者: Dong Wang, Yuren Wei, Melinda Frye, Christopher L. Gentile, Michael J. Pagliassotti
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Limited 2013-01-01
シリーズ:Journal of Nutrition and Metabolism
オンライン・アクセス:http://dx.doi.org/10.1155/2013/514206
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