The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

Epithelial to mesenchymal transition (EMT) is implicated in the progression of primary tumours towards metastasis and is likely caused by a pathological activation of transcription factors regulating EMT in embryonic development. To analyse EMT-causing pathways in tumouri-genesis, we identified tran...

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Hauptverfasser: Aigner, K, Dampier, B, Descovich, L, Mikula, M, Sultan, A, Schreiber, M, Mikulits, W, Brabletz, T, Strand, D, Obrist, P, Sommergruber, W, Schweifer, N, Wernitznig, A, Beug, H, Foisner, R, Eger, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899859/
https://ncbi.nlm.nih.gov/pubmed/17486063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210508
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