The transcription factor ZEB1 (δEF1) represses Plakophilin 3 during human cancer progression

Plakophilin 3 (PKP3) belongs to the p120ctn family of armadillo-related proteins predominantly functioning in desmosome formation. Here we report that PKP3 is transcriptionally repressed by the E-cadherin repressor ZEB1 in metastatic cancer cells. ZEB1 physically associates with two conserved E-box...

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Hlavní autoři: Aigner, Kirsten, Descovich, Luise, Mikula, Mario, Sultan, Aneesa, Dampier, Brigitta, Bonné, Stefan, van Roy, Frans, Mikulits, Wolfgang, Schreiber, Martin, Brabletz, Thomas, Sommergruber, Wolfgang, Schweifer, Norbert, Wernitznig, Andreas, Beug, Hartmut, Foisner, Roland, Eger, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938730/
https://ncbi.nlm.nih.gov/pubmed/17391671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.03.026
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