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The transcription factor ZEB1 (δEF1) represses Plakophilin 3 during human cancer progression
Plakophilin 3 (PKP3) belongs to the p120ctn family of armadillo-related proteins predominantly functioning in desmosome formation. Here we report that PKP3 is transcriptionally repressed by the E-cadherin repressor ZEB1 in metastatic cancer cells. ZEB1 physically associates with two conserved E-box...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938730/ https://ncbi.nlm.nih.gov/pubmed/17391671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.03.026 |
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