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Improving sensitivity in proteome studies by analysis of false discovery rates for multiple search engines
Tandem mass spectrometry, run in combination with liquid chromatography (LC-MS/MS), can generate large numbers of peptide and protein identifications, for which a variety of database search engines are available. Distinguishing correct identifications from false positives is far from trivial because...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2899855/ https://ncbi.nlm.nih.gov/pubmed/19253293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800473 |
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