Double-strand breaks repair in lymphoblastoid cell lines from sisters discordant for breast cancer from the New York site of the BCFR

Unrepaired DNA double-strand breaks (DSBs) may have serious consequences for cells by inducing chromosomal aberrations, thereby increasing genetic instability and cancer risk. One's capacity to repair DSB is therefore an important factor to consider when estimating cancer risk. We assessed DNA...

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Главные авторы: Machella, Nicola, Terry, Mary Beth, Zipprich, Jennifer, Gurvich, Irina, Liao, Yuyan, Senie, Ruby T., Kennedy, David O., Santella, Regina M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
Предметы:
Molecular Epidemiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899852/
https://ncbi.nlm.nih.gov/pubmed/18566018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn140
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