A Phase I Study of an Oral Simulated FOLFOX with High Dose Capecitabine

BACKGROUND: A phase I study of high-dose capecitabine given over 2 days, along with oxaliplatin, bolus 5FU and leucovorin (LV), was designed to simulate FOLFOX6 without the need for infusional 5FU. METHODS: Schedule A included oxaliplatin 100 mg/m(2), 5FU 400 mg/m(2), and LV 20 mg/m(2) (all given IV...

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Main Authors: Mulkerin, D., LoConte, N.K., Holen, K.D., Thomas, J.P., Alberti, D., Marnocha, R., Kolesar, J., Eickhoff, J., Oliver, K., Feierabend, C., Wilding, G.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899673/
https://ncbi.nlm.nih.gov/pubmed/19129971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-008-9210-8
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