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A phase I study of sorafenib, oxaliplatin and two days of high dose capecitabine in advanced pancreatic and biliary tract cancer: A Wisconsin Oncology Network Study

Chemotherapy has yielded minimal clinical benefit in pancreatic and biliary tract cancer. A high-dose, short course capecitabine schedule with oxaliplatin, has shown some efficacy with a lower incidence of palmar-plantar erythrodysesthesia. Achieving high exposures of the targeted agent sorafenib ma...

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Detalhes bibliográficos
Main Authors: LoConte, Noelle K., Holen, Kyle D., Schelman, William R., Mulkerin, Daniel L., Deming, Dustin A., Hernan, Hilary R., Traynor, Anne M., Goggins, Timothy, Groteluschen, David, Oettel, Kurt, Robinson, Emily, Lubner, Sam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199231/
https://ncbi.nlm.nih.gov/pubmed/23263993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-012-9916-5
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