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Sustained long-term RNA interference in nucleus pulposus cells in vivo mediated by unmodified small interfering RNA

RNA interference (RNAi) technology has recently emerged as an important biological strategy for gene silencing. Previously, the efficacies of RNAi in cultured nucleus pulposus cells in vitro have been reported. However, RNAi in the disc in vivo has never been reported. Therefore, the aims of the pre...

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Bibliografiske detaljer
Main Authors: Suzuki, Teppei, Nishida, Kotaro, Kakutani, Kenichiro, Maeno, Koichiro, Yurube, Takashi, Takada, Toru, Kurosaka, Masahiro, Doita, Minoru
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899333/
https://ncbi.nlm.nih.gov/pubmed/19142673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-008-0873-9
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