Complete Analysis of the Human Mesotrypsinogen Gene (PRSS3) in Patients with Chronic Pancreatitis

BACKGROUND/AIMS: A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of chronic pancreatitis (CP). Mesotrypsin (PRSS3) can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activ...

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Main Authors: Rosendahl, Jonas, Teich, Niels, Kovacs, Peter, Szmola, Richard, Blüher, Matthias, Gress, Thomas M., Hoffmeister, Albrecht, Keim, Volker, Löhr, Matthias, Mössner, Joachim, Nickel, Renate, Ockenga, Johann, Pfützer, Roland, Schulz, Hans-Ulrich, Stumvoll, Michael, Wittenburg, Henning, Sahin-Tóth, Miklós, Witt, Heiko
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2010
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Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899151/
https://ncbi.nlm.nih.gov/pubmed/20484962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000243769
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