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Complete Analysis of the Human Mesotrypsinogen Gene (PRSS3) in Patients with Chronic Pancreatitis

BACKGROUND/AIMS: A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of chronic pancreatitis (CP). Mesotrypsin (PRSS3) can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activ...

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Detalhes bibliográficos
Main Authors: Rosendahl, Jonas, Teich, Niels, Kovacs, Peter, Szmola, Richard, Blüher, Matthias, Gress, Thomas M., Hoffmeister, Albrecht, Keim, Volker, Löhr, Matthias, Mössner, Joachim, Nickel, Renate, Ockenga, Johann, Pfützer, Roland, Schulz, Hans-Ulrich, Stumvoll, Michael, Wittenburg, Henning, Sahin-Tóth, Miklós, Witt, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899151/
https://ncbi.nlm.nih.gov/pubmed/20484962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000243769
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