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Dominant Negative p38 Mitogen-Activated Protein Kinase Expression Inhibits NF-κB Activation in AR42J Cells

BACKGROUND: The role of the p38 mitogen-activated protein (MAP) kinase in acute pancreatitis pathogenesis is controversial. We hypothesize that p38 plays a role in regulating NF-κB activation in exocrine pancreatic cells. METHODS: AR42J cells incorporating an NF-κB-responsive luciferase reporter, wi...

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Detalhes bibliográficos
Main Authors: Twait, Erik, Williard, Deborah E., Samuel, Isaac
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899148/
https://ncbi.nlm.nih.gov/pubmed/20453549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000290656
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