The conserved Bardet-Biedl Syndrome proteins assemble a coat that traffics membrane proteins to cilia

The BBSome is a complex of Bardet-Biedl Syndrome (BBS) proteins that shares common structural elements with COPI, COPII and clathrin coats. Here we show that the BBSome constitutes a coat complex that sorts membrane proteins to primary cilia. Biochemically, the BBSome is the major effector of the Ar...

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Main Authors: Jin, Hua, White, Susan Roehl, Shida, Toshinobu, Schulz, Stefan, Aguiar, Mike, Gygi, Steven P., Bazan, J. Fernando, Nachury, Maxence V.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898735/
https://ncbi.nlm.nih.gov/pubmed/20603001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.015
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