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Bardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

Primary cilia are ubiquitous cellular appendages that provide important yet not well understood sensory and signaling functions. Ciliary dysfunction underlies numerous human genetic disorders. However, the precise defects in cilia function and the basis of disease pathophysiology remain unclear. Her...

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Detalhes bibliográficos
Main Authors: Berbari, Nicolas F., Lewis, Jacqueline S., Bishop, Georgia A., Askwith, Candice C., Mykytyn, Kirk
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393805/
https://ncbi.nlm.nih.gov/pubmed/18334641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711027105
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