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Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources

BACKGROUND: We use silkworms to evaluate therapeutic effects of drug candidates. Our previous reports have revealed that there are common mechanisms of pharmacokinetics of chemicals in silkworms and mammals. In this report, we attempt to establish a method by using silkworms to identify chemicals fr...

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Detalhes bibliográficos
Main Authors: Asami, Yukihiro, Horie, Ryo, Hamamoto, Hiroshi, Sekimizu, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898707/
https://ncbi.nlm.nih.gov/pubmed/20537191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-10-7
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