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Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources

BACKGROUND: We use silkworms to evaluate therapeutic effects of drug candidates. Our previous reports have revealed that there are common mechanisms of pharmacokinetics of chemicals in silkworms and mammals. In this report, we attempt to establish a method by using silkworms to identify chemicals fr...

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Autors principals: Asami, Yukihiro, Horie, Ryo, Hamamoto, Hiroshi, Sekimizu, Kazuhisa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898707/
https://ncbi.nlm.nih.gov/pubmed/20537191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-10-7
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