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Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice

Allogeneic hematopoietic stem cell transplantation (HSCT) is used effectively to treat a number of hematological malignancies. Its beneficial effects rely on donor-derived T cell–targeted leukemic cells, the so-called graft-versus-leukemia (GVL) effect. Induction of GVL is usually associated with co...

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Detalhes bibliográficos
Main Authors: Asakura, Shoji, Hashimoto, Daigo, Takashima, Shuichiro, Sugiyama, Haruko, Maeda, Yoshinobu, Akashi, Koichi, Tanimoto, Mitsune, Teshima, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898583/
https://ncbi.nlm.nih.gov/pubmed/20530875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39165
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