TARGETED INHIBITION OF mTOR SIGNALING INHIBITS TUMORIGENESIS OF COLORECTAL CANCER

PURPOSE: The mammalian target of rapamycin (mTOR) kinase acts downstream of PI3K/Akt to regulate cellular growth, metabolism and cytoskeleton. Since approximately 60% of sporadic colorectal cancers (CRCs) exhibit high levels of activated Akt, we determined whether downstream mTOR signaling pathway c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gulhati, Pat, Cai, Qingsong, Li, Jing, Liu, Jianyu, Rychahou, Piotr G., Qiu, Suimin, Lee, Eun Y., Silva, Scott R., Bowen, Kanika A., Gao, Tianyan, Evers, B. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898570/
https://ncbi.nlm.nih.gov/pubmed/19934294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1249
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados