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Induced-fit Mechanism for Prolyl Endopeptidase
Prolyl peptidases cleave proteins at proline residues and are of importance for cancer, neurological function, and type II diabetes. Prolyl endopeptidase (PEP) cleaves neuropeptides and is a drug target for neuropsychiatric diseases such as post-traumatic stress disorder, depression, and schizophren...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898448/ https://ncbi.nlm.nih.gov/pubmed/20444688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092692 |
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