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CR6-interacting Factor 1 (CRIF1) Regulates NF-E2-related Factor 2 (NRF2) Protein Stability by Proteasome-mediated Degradation

Free radicals generated by oxidative stress cause damage that can contribute to numerous chronic diseases. Mammalian cells respond to this damage by increased transcription of cytoprotective phase II genes, which are regulated by NRF2. Previously, it has been shown that NRF2 protein levels increase...

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Sonraí Bibleagrafaíochta
Main Authors: Kang, Hyo Jin, Hong, Young Bin, Kim, Hee Jeong, Bae, Insoo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898415/
https://ncbi.nlm.nih.gov/pubmed/20427290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084590
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