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Mutagenesis Reveals the Complex Relationships between ATPase Rate and the Chaperone Activities of Escherichia coli Heat Shock Protein 70 (Hsp70/DnaK)

The Escherichia coli 70-kDa heat shock protein, DnaK, is a molecular chaperone that engages in a variety of cellular activities, including the folding of proteins. During this process, DnaK binds its substrates in coordination with a catalytic ATPase cycle. Both the ATPase and protein folding activi...

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Hlavní autoři: Chang, Lyra, Thompson, Andrea D., Ung, Peter, Carlson, Heather A., Gestwicki, Jason E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898401/
https://ncbi.nlm.nih.gov/pubmed/20439464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.124149
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