Calcium/Calmodulin-dependent Protein Kinase II Delta 6 (CaMKIIδ(6)) and RhoA Involvement in Thrombin-induced Endothelial Barrier Dysfunction

Multiple Ca(2+) release and entry mechanisms and potential cytoskeletal targets have been implicated in vascular endothelial barrier dysfunction; however, the immediate downstream effectors of Ca(2+) signals in the regulation of endothelial permeability still remain unclear. In the present study, we...

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Detalhes bibliográficos
Main Authors: Wang, Zhen, Ginnan, Roman, Abdullaev, Iskandar F., Trebak, Mohamed, Vincent, Peter A., Singer, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898399/
https://ncbi.nlm.nih.gov/pubmed/20442409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.120790
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