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Role of External Loops of Human Ceruloplasmin in Copper Loading by ATP7B and Ccc2p
Ceruloplasmin is a multicopper oxidase required for correct iron homeostasis.Previously, we have identified a ceruloplasmin mutant associated with the iron overload disease aceruloplasminemia, which was unable to acquire copper from the mammalian pump ATP7B but could be produced in an enzymatically...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898344/ https://ncbi.nlm.nih.gov/pubmed/20430895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.090027 |
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