Novel Approach to Probe Subunit-specific Contributions to N-Methyl-d-aspartate (NMDA) Receptor Trafficking Reveals a Dominant Role for NR2B in Receptor Recycling

N-Methyl-d-aspartate (NMDA) receptors are expressed at excitatory synapses throughout the brain and are essential for neuronal development and synaptic plasticity. Functional NMDA receptors are tetramers, typically composed of NR1 and NR2 subunits (NR2A–D). NR2A and NR2B are expressed in the forebra...

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Detalhes bibliográficos
Main Authors: Tang, Tina Tze-Tsang, Badger, John D., Roche, Paul A., Roche, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898322/
https://ncbi.nlm.nih.gov/pubmed/20427279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102210
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