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Structure of a Class I Tagatose-1,6-bisphosphate Aldolase: INVESTIGATION INTO AN APPARENT LOSS OF STEREOSPECIFICITY

Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes is a class I aldolase that exhibits a remarkable lack of chiral discrimination with respect to the configuration of hydroxyl groups at both C3 and C4 positions. The enzyme catalyzes the reversible cleavage of four diastereoisomers (fruct...

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Detalhes bibliográficos
Main Authors: LowKam, Clotilde, Liotard, Brigitte, Sygusch, Jurgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898290/
https://ncbi.nlm.nih.gov/pubmed/20427286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080358
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