Entamoeba histolytica sirtuin EhSir2a deacetylates tubulin and regulates the number of microtubular assemblies during the cell cycle

We have discovered four sirtuin genes in Entamoeba histolytica, two of which are similar to eukaryotic sirtuins and two to bacterial and archaeal sirtuins. The eukaryotic sirtuin homolog, EhSir2a showed NAD(+) dependent deacetylase activity and was sensitive to Class III HDAC inhibitors. Localizatio...

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Bibliographic Details
Main Authors:	Dam, Somasri, Lohia, Anuradha
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2897950/ https://ncbi.nlm.nih.gov/pubmed/20148900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01449.x
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Entamoeba histolytica sirtuin EhSir2a deacetylates tubulin and regulates the number of microtubular assemblies during the cell cycle

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