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EhRho1, a RhoA-Like GTPase of Entamoeba histolytica, Is Modified by Clostridial Glucosylating Cytotoxins

Clostridial glucosylating cytotoxins inactivate mammalian Rho GTPases by mono-O glucosylation of a conserved threonine residue located in the switch 1 region of the target protein. Here we report that EhRho1, a RhoA-like GTPase from the protozoan parasite Entamoeba histolytica, is glucosylated by cl...

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Detalhes bibliográficos
Main Authors: Majumder, Shubhra, Schmidt, Gudula, Lohia, Anuradha, Aktories, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694214/
https://ncbi.nlm.nih.gov/pubmed/17056697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01826-06
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