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IL-17RC is required for immune signaling via an extended SEFIR domain in the cytoplasmic tail
IL-17 mediates essential inflammatory responses in host defense and autoimmunity. The IL-17A/IL-17F signaling complex is composed of IL-17RA and IL-17RC, both of which are necessary for signal transduction. To date, the specific contribution of IL-17RC to downstream signaling remains poorly understo...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897912/ https://ncbi.nlm.nih.gov/pubmed/20554964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903739 |
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