Targeted Deletion of Kcne2 Causes Gastritis Cystica Profunda and Gastric Neoplasia

Gastric cancer is the second leading cause of cancer death worldwide. Predisposing factors include achlorhydria, Helicobacter pylori infection, oxyntic atrophy and TFF2-expressing metaplasia. In parietal cells, apical potassium channels comprising the KCNQ1 α subunit and the KCNE2 β subunit provide...

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Autori principali: Roepke, Torsten K., Purtell, Kerry, King, Elizabeth C., La Perle, Krista M. D., Lerner, Daniel J., Abbott, Geoffrey W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897890/
https://ncbi.nlm.nih.gov/pubmed/20625512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011451
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