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Targeted Deletion of Kcne2 Causes Gastritis Cystica Profunda and Gastric Neoplasia

Gastric cancer is the second leading cause of cancer death worldwide. Predisposing factors include achlorhydria, Helicobacter pylori infection, oxyntic atrophy and TFF2-expressing metaplasia. In parietal cells, apical potassium channels comprising the KCNQ1 α subunit and the KCNE2 β subunit provide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Roepke, Torsten K., Purtell, Kerry, King, Elizabeth C., La Perle, Krista M. D., Lerner, Daniel J., Abbott, Geoffrey W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897890/
https://ncbi.nlm.nih.gov/pubmed/20625512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011451
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